Emily Spence Davizon, MPH; Therese Pilonetti, REHS, CP-FS; and Sara Lopez, RN, BSN, MPH from the Colorado Department of Public Health and Environment (CDPHE) presented an overview on the state of monkeypox in Colorado followed by a Q&A session to answer specific questions. Healthcare providers, public health professionals, vaccine advocates, health educators, school nurses, community leaders, and anyone else interested in monkeypox in Colorado will all benefit from the information shared on this topic.